Orthobiologics are natural therapies derived from your own blood or tissue that promote healing by enhancing the body's repair processes at the cellular level. Treatments like Platelet-Rich Plasma (PRP), Bone Marrow Aspirate Concentrate (BMAC), and A2M help regenerate damaged tissues, reduce inflammation, and improve circulation, offering a non-surgical, minimally invasive option for musculoskeletal injuries, chronic pain, and more. These therapies support faster recovery and restore function naturally, using your body’s own healing power.






Orthobiologics are substances derived from your own blood or tissue that help your body heal. When processed and injected into damaged or inflamed areas, they stimulate the body’s natural repair processes at the cellular level. Common types of orthobiologic therapies include:
Platelet-Rich Plasma (PRP): Concentrated platelets that release growth factors to repair tissue and improve circulation.
Platelet Lysate or PRGF: A refined form of PRP with anti-inflammatory growth factors for nerve, tendon, and soft-tissue healing.
Bone Marrow Aspirate Concentrate (BMAC): Stem-cell-rich marrow from your pelvis that regenerates deeper or chronic injuries.
A2M (Alpha-2-Macroglobulin): A plasma protein that helps block enzymes that cause cartilage breakdown and inflammation.
Each treatment is personalized to your specific diagnosis, tissue type, and activity level.
How Orthobiologic Injections Work
Your Sample: A small amount of your blood or bone marrow is collected in a sterile procedure.
Processing: The sample is centrifuged to isolate the most potent growth factors or cells.
Guided Injection: Using ultrasound or fluoroscopic imaging, your physician injects the biologic directly into the injured tissue.
Regeneration: The biologic signals trigger healing, reduce inflammation, and stimulate stronger, healthier tissue growth over time.
Healing occurs naturally from within, using your body’s own cells.
Conditions Treated with Orthobiologic Therapy
Orthobiologic injections can treat a variety of musculoskeletal conditions, including:
Tendon injuries (e.g., tennis elbow, Achilles tendonitis, rotator cuff tears)
Ligament sprains and partial tears
Joint degeneration (knee, hip, shoulder, spine)
Chronic muscle or fascia pain
Post-injury or post-surgical healing
Plantar fasciitis and foot/ankle pain
Early arthritis or cartilage wear
Orthobiologic injections work well when combined with other treatments like osteopathic manipulation, shockwave therapy, or laser therapy to enhance circulation and healing.
Benefits of Orthobiologic Injections
Natural healing using your own cells
Non-surgical, minimally invasive procedure
Reduces inflammation and pain
Restores strength and motion
Helps delay or avoid joint surgery
Complements physical therapy and other integrative treatments
Most patients resume normal activities quickly, with improvements building over several weeks as tissue regeneration progresses.
Integrative Healing Approach
At Total Integrative, we take a comprehensive approach to your recovery. Your treatment may include:
Hormone and nutritional optimization to support tissue repair
Shockwave or 1064-laser therapy to improve blood flow
Targeted supplements for joint and collagen health
Osteopathic manipulation or rehabilitation for functional recovery
This holistic approach addresses not only the site of pain but also the underlying factors affecting healing, such as circulation, inflammation, and tissue integrity.
What to Expect
Consultation: We assess your condition, imaging, and health profile to determine the best treatment.
Procedure: In-office, image-guided injections are performed with local anesthesia, ensuring minimal discomfort.
Recovery: Mild soreness may occur for 24–48 hours. Avoid anti-inflammatory medications to support healing.
Results: Improvement typically begins within 3–6 weeks and continues over several months as tissue regenerates.
Discover the Power of Regenerative Healing
Orthobiologic injections offer a safe, evidence-based method to restore function, reduce pain, and promote natural healing.
Schedule a consultation to see if orthobiologic therapy is right for you and start your journey toward lasting recovery.
23101 Lake Center Drive, Suite 315
Lake Forest, California 92630
United States
Phone: (562) 546-2811
Email: [email protected]
Tuesday: 9:00 AM - 5:00 PM
Wednesday: 9:00 AM - 5:00 PM
Thursday: 9:00 AM - 5:00 PM
23101 Lake Center Drive, Suite 315
Lake Forest, California 92630
United States
Phone: (562) 546-2811
Fax: (810) 202-7549
Email: [email protected]
Tuesday: 9:00 AM - 5:00 PM
Wednesday: 9:00 AM - 5:00 PM
Thursday: 9:00 AM - 5:00 PM
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