
Orthobiologics are natural therapies derived from your own blood or tissue that promote healing by enhancing the body's repair processes at the cellular level. Treatments like Platelet-Rich Plasma (PRP), Bone Marrow Aspirate Concentrate (BMAC), and A2M help regenerate damaged tissues, reduce inflammation, and improve circulation, offering a non-surgical, minimally invasive option for musculoskeletal injuries, chronic pain, and more. These therapies support faster recovery and restore function naturally, using your body’s own healing power.






Orthobiologics are substances derived from your own blood or tissue that help your body heal. When carefully processed and injected into damaged or inflamed areas, they enhance the body’s natural repair processes at the cellular level.
Common types of orthobiologic therapies include:
Platelet-Rich Plasma (PRP): Concentrated platelets that release growth factors to repair tissue and improve circulation.
Platelet Lysate or PRGF: A refined form of PRP containing anti-inflammatory growth factors for nerve, tendon, and soft-tissue healing.
Bone Marrow Aspirate Concentrate (BMAC): Uses stem-cell-rich marrow from your pelvis to regenerate deeper or more chronic injuries.
A2M (Alpha-2-Macroglobulin): A plasma protein that helps block enzymes that cause cartilage breakdown and inflammation.
Each treatment is tailored to your specific diagnosis, tissue type, and activity level.
Your Sample: A small amount of your blood or bone marrow is collected in a sterile process.
Processing: The sample is centrifuged to isolate the most potent growth factors or cells.
Guided Injection: Using precise ultrasound or fluoroscopic imaging, your physician injects the prepared biologic directly into the injured tissue.
Regeneration: The biologic signals trigger healing, reduce inflammation, and stimulate the growth of stronger, healthier tissue over time.
Healing happens from within — using your body’s own natural chemistry.
Tendon injuries (tennis elbow, Achilles tendonitis, rotator cuff tears)
Ligament sprains and partial tears
Joint degeneration (knee, hip, shoulder, spine)
Chronic muscle or fascia pain
Post-injury or post-surgical healing
Plantar fasciitis and foot/ankle pain
Early arthritis or cartilage wear
Orthobiologic injections are particularly effective when combined with osteopathic manipulation, shockwave therapy, or laser therapy to enhance circulation and healing.
Natural healing using your own cells
Non-surgical, minimally invasive
Reduces inflammation and pain
Restores strength and motion
Helps delay or avoid joint surgery
Complements physical therapy and integrative treatments
Most patients resume normal activities quickly, with improvements building gradually over several weeks as tissue regeneration continues.
At Total Integrative, orthobiologic injections are never performed in isolation.
Your program may include:
Hormone & nutritional optimization to enhance tissue repair
Shockwave or 1064-laser therapy for improved blood flow
Targeted supplements to support joint and collagen health
Osteopathic manipulation or rehabilitation therapy for functional recovery
This whole-body approach addresses not just the site of pain, but the underlying drivers of poor healing — circulation, inflammation, and tissue integrity.
Consultation: We assess your condition, imaging, and health profile to determine the best biologic option.
Procedure: In-office, image-guided injections are performed with local anesthesia and minimal discomfort.
Recovery: Expect mild soreness for 24–48 hours; avoid anti-inflammatory medications to support healing.
Results: Improvements typically begin within 3–6 weeks and continue over several months as tissue regenerates.
Orthobiologic injections offer a safe, evidence-based way to restore function, reduce pain, and help your body heal naturally.
Schedule a consultation to see if orthobiologic therapy is right for your musculoskeletal condition — and take the next step toward lasting, regenerative recovery.
23101 Lake Center Drive, Suite 315
Lake Forest, California 92630
United States
Phone: (562) 546-2811
Fax: (810) 202-7549
Email: [email protected]
Tuesday: 9:00 AM - 5:00 PM
Wednesday: 9:00 AM - 5:00 PM
Thursday: 9:00 AM - 5:00 PM
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23101 Lake Center Drive, Suite 315
Lake Forest, California 92630
United States
Phone: (562) 546-2811
Fax: (810) 202-7549
Email: [email protected]
Tuesday: 9:00 AM - 5:00 PM
Wednesday: 9:00 AM - 5:00 PM
Thursday: 9:00 AM - 5:00 PM
Join our newsletter for personalized wellness insights and care updates.
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